Further options for your experiments:
Application schemes and assay conditions can be adapted to your needs.
Whole-cell recordings or single-channel analysis in various expression systems
(HEK 293, CHO, Neuroblastoma etc.) can be conducted to test the effects of drugs on voltage-gated or ligand-gated ion channels.
B'SYS currently operates 4 automated patch clamp devices (Sophion Qpatch™).
Please contact us for details or offers → Contact
| Target | Gene | Species | Disorder | Manual | Automated | ||
|---|---|---|---|---|---|---|---|
| CaV1.2 | CACNA1C/CACNB2/ CACNA2D | human | Autism / Heart function / Psychiatric Disorders | 0 | 0 |
|
 |
| CaV1.2 / peak current | CACNA1C/CACNB2/ CACNA2D | human | Autism / Heart function / Psychiatric Disorders | 0 | 1 | |
|
| CaV1.3 | CACNA1D / CACNB3 / CACNA2D | human | 0 | 0 | |
||
| CaV2.1 | CACNA1A / CACNB3 / CACNA2D2 or CACNA2D4 | human | Ataxia / Epilepsy / Migraine | 0 | 1 | |
|
| CaV3.1 | CACNA1G | human | Cognition | 0 | 1 |
|
|
| CaV3.2 | CACNA1H | human | Epilepsy / Pain | 0 | 0 | |
|
| CaV3.3 | CACNA1I | human | 0 | 1 | |
||
| CaV3.3 | CACNA1I | human | 0 | 1 | |
||
| Neuroblastoma whole calcium (T- and L- type) | 0 | 0 | |