Further options for your experiments:
Application schemes and assay conditions can be adapted to your needs.
Whole-cell recordings or single-channel analysis in various expression systems
(HEK 293, CHO, Neuroblastoma etc.) can be conducted to test the effects of drugs on voltage-gated or ligand-gated ion channels.
B'SYS currently operates 4 automated patch clamp devices (Sophion Qpatch™).
Please contact us for details or offers → Contact
| Target | Gene | Species | Disorder | Manual | Automated | ||
|---|---|---|---|---|---|---|---|
| AMPA | GRIA1 | human | Cognition / Psychiatric Disorders | 0 | 1 |  |
|
| Kainate K1 | GRIK1 | human | Seizure disorders | 0 | 1 | |
|
| Kainate K2 | GRIK2 | human | Epilepsy | 0 | 0 | |
|
| Kainate K2 | GRIK2 | human | Epilepsy | 0 | 0 |
|
|
| Kainate K2/K5 | GRIK2 / GRIK5 | human | 0 | 1 | |
||
| NMDA (NR1 / 2A) | GRIN1 / GRIN2A | human | Epilepsy / Psychiatric Disorders | 0 | 0 |
|
|
| NMDA (NR1 / 2B) | GRIN1 / GRIN2B | human | Depression | 0 | 0 |
|
|
| NMDA (NR1 / 2C) | GRIN1 / GRIN2C | human | 0 | 1 | |
||
| NMDA (NR1 / 2D) | GRIN1 / GRIN2D | human | Seizure disorders | 0 | 1 |
|
|