| Target | Gene | Species | Disorder | Cell Type | Expression | ||
|---|---|---|---|---|---|---|---|
| nAChR α4β2 | CHRNA4 / CHRNB2 | human | Cognition | CHO | constitutive |
|
 |
| Target | Gene | Species | Disorder | Cell Type | Expression | ||
|---|---|---|---|---|---|---|---|
| GABAA α1β2γ2 | GABRA1 / GABRB2 / GABRG2 | human | Psychiatric Disorders | CHO | constitutive |
|
|
| GABAA α2β2γ2 | GABRA2 / GABRB2 / GABRG2 | human | Psychiatric Disorders | HEK 293 | inducible | |
| Target | Gene | Species | Disorder | Cell Type | Expression | ||
|---|---|---|---|---|---|---|---|
| Kainate K2 | GRIK2 | human | Epilepsy | CHO | constitutive | |
|
| Kainate K2 | GRIK2 | human | Epilepsy | HEK 293 | inducible |
|
|
| NMDAR1 | GRIN1 | human | Mental retardation | HEK 293 | inducible |
|
|
| NMDA (NR1 / 2A) | GRIN1 / GRIN2A | human | Epilepsy / Psychiatric Disorders | HEK 293 | inducible |
|
|
| NMDA (NR1 / 2B) | GRIN1 / GRIN2B | human | Depression | HEK 293 | inducible |
|
|
| NMDA (NR1 / 2D) | GRIN1 / GRIN2D | human | Seizure disorders | HEK 293 | inducible |
|
|
| Target | Gene | Species | Disorder | Cell Type | Expression | ||
|---|---|---|---|---|---|---|---|
| GlyRα1 | GLRA1 | human | Pain sensation | CHO | constitutive |
|
|
| GlyRα2 | GLRA2 | human | Epilepsy | CHO | constitutive |
|
|
| GlyRα3 | GLRA3 | human | Pain sensation | HEK 293 | inducible | |
|
| GlyRα3 | GLRA3 | rat | Pain sensation | CHO | constitutive | |
|
| GlyRα3 | GLRA3 | human | Pain sensation | CHO | constitutive |
|
|
| Target | Gene | Species | Disorder | Cell Type | Expression | ||
|---|---|---|---|---|---|---|---|
| 5HT3A | 5HT3A | human | Psychiatric Disorders | CHO | constitutive | |
| Target | Gene | Species | Disorder | Cell Type | Expression | ||
|---|---|---|---|---|---|---|---|
| ASIC1a long | ACCN2 | human | Pain | CHO | constitutive | |
|
| ASIC1a short | ACCN2 | human | Pain | CHO | constitutive | |
|
| ASIC1b | ACCN2 | human | Pain | CHO | constitutive | |
|
| ASIC2 | ACCN1 | human | Epilepsy / Migraine / Pain | CHO | constitutive | |
| Target | Gene | Species | Disorder | Cell Type | Expression | ||
|---|---|---|---|---|---|---|---|
| P2X1 | P2rx1 | human | Immune system related | CHO | constitutive |
|
|
| P2X2 | P2rx2 | human | CHO | constitutive |
|
|
|
| P2X2/3 | P2rx2/P2rx3 | human | Pain | CHO | constitutive |
|
|
| P2X3 | P2rx3 | human | Pain | CHO | constitutive |
|
|
| P2X4 | P2rx4 | human | Immune system related | HEK 293 | constitutive |
|
|
| P2X7 | P2rx7 | human | Neuroinflammation | HEK 293 | constitutive |
|
|