Cell Lines

Stable cell line generation

Voltage gated ion channels (VGIC)

Potassium

Target Gene Species Disorder Cell Type Expression    
KV1.1 KCNA1 human Seizure disorders CHO constitutive
KV1.2 KCNA2 human Seizure disorders CHO constitutive
KV1.3 KCNA3 human Immune system related CHO constitutive
KV1.4 KCNA4 human Autoimmune diseases CHO constitutive
KV1.5 KCNA5 human Heart function CHO constitutive
KV1.6 KCNA6 human Seizure disorders CHO constitutive
KV1.7 KCNA7 human Heart function CHO constitutive
KV2.1 KCNB1 human Seizure disorders CHO constitutive
KV2.1 KCNB1 human Seizure disorders HEK 293 inducible
KV2.2 KCNB2 human Seizure disorders CHO constitutive
KV2.2 KCNB2 human Seizure disorders HEK 293 inducible
KV3.1a (short) KCNC1 human Autism / Epilepsy / Pain / Psychiatric Disorders CHO constitutive
KV3.1b (long) KCNC1 human Autism / Epilepsy / Pain / Psychiatric Disorders CHO constitutive
KV3.2 KCNC2 human Epilepsy / Pain / Psychiatric Disorders CHO inducible
KV3.3 KCNC3 human Hearing disorders / Spinocerebellar ataxia CHO constitutive
KV3.4 KCNC4 human Neurodegeneration CHO inducible
KV4.2 KCND2 human Seizure disorders CHO constitutive
KV4.3 KCND3 human Heart function CHO constitutive
KV4.3 KCND3 human Heart function HEK 293 inducible
KV4.3 KChip KCND3 human Heart function CHO constitutive
KV7.1 (KVLQT1) / minK KCNQ1 / KCNE1 human LQT Syndrome HEK 293 constitutive
KV7.1 (KVLQT1) KCNQ1 human LQT Syndrome CHO constitutive
KV7.1 (KVLQT1) KCNQ1 human LQT Syndrome HEK 293 inducible
KV7.1 (KVLQT1) KCNQ1 human LQT Syndrome 1/5 HEK 293 constitutive
KV7.1 (KVLQT1) / minK KCNQ1/KCNE1 human LQT Syndrome 1/5 HEK 293 constitutive
KV7.1 (KVLQT1) / minK KCNQ1/KCNE1 human LQT Syndrome 1/5 CHO constitutive
KV7.2 KCNQ2 human Epilepsy CHO constitutive
KV7.3 KCNQ3 human Epilepsy CHO constitutive
KV7.2/3 KCNQ2 / KCNQ3 rat Epilepsy CHO constitutive
KV7.2/3 KCNQ2 / KCNQ3 human Epilepsy CHO constitutive
KV10.1 KCNH1 human Cancer CHO constitutive
KV11.1 (hERG DUO) KCNH2 human LQT Syndrome 2 CHO constitutive
KV11.1 (hERG) KCNH2 human LQT Syndrome 2 CHO constitutive
KV11.1 (hERG) KCNH2 human LQT Syndrome 2 CHO inducible
KV11.1 (hERG) KCNH2 human LQT Syndrome 2 HEK 293 constitutive
KV11.1 (hERG) KCNH2 human LQT Syndrome 2 HEK 293 inducible
Kir1.1 KCNJ1 human CHO constitutive
Kir2.1 KCNJ2 human LQT Syndrome CHO constitutive
Kir2.3 KCNJ4 human LQT Syndrome 9 HEK 293 constitutive
Kir2.3 KCNJ4 human LQT Syndrome 9 CHO constitutive
BK α1 KCNMA1 human Epilepsy / Pain CHO constitutive
BK α1 KCNMA1 human Epilepsy / Pain HEK 293 inducible
BK α1β2 KCNMA1 / KCNMB2 human Autism / Seizure disorders CHO inducible
BK α1β4 KCNMA1 / KCNMB4 human Seizure disorders CHO inducible
SK2, KCa2.2 KCNN2 human Heart function / Seizure disorders CHO inducible
SK1 / SK2, KCa2.1 / KCa2.2 KCNN1 / KCNN2 human CHO inducible
SK4, KCa3.1 KCNN4 human Heart function CHO constitutive
K2P18.1 KCNK18 human Pain HEK 293 constitutive
KCa4.1 KCNT1 human Seizure disorders CHO inducible