Cell Lines

Stable cell line generation

Ligand gated ion channels

Glutamate

Target Gene Species Disorder Cell Type Expression    
Kainate K2 GRIK2 human Epilepsy CHO constitutive
Kainate K2 GRIK2 human Epilepsy HEK 293 inducible
NMDAR1 GRIN1 human Mental retardation HEK 293 inducible
NMDA (NR1 / 2A) GRIN1 / GRIN2A human Epilepsy / Psychiatric Disorders HEK 293 inducible
NMDA (NR1 / 2B) GRIN1 / GRIN2B human Depression HEK 293 inducible
NMDA (NR1 / 2D) GRIN1 / GRIN2D human Seizure disorders HEK 293 inducible