| Target | Gene | Species | Disorder | Cell Type | Expression | ||
|---|---|---|---|---|---|---|---|
| NaV1.1 | SCN1A | human | Epilepsy | CHO | constitutive |  |
|
| NaV1.2 | SCN2A | human | Autism / Epilepsy / Intellectual disability | CHO | constitutive |
|
|
| NaV1.3 | SCN3A | human | Epilepsy / Pain | CHO | constitutive | |
|
| NaV1.4 | SCN4A | human | Myotonia | HEK 293 | inducible |
|
|
| NaV1.4 | SCN4A | human | Myotonia | CHO | constitutive |
|
|
| NaV1.5 | SCN5A | human | LQT Syndrome 3 | HEK | inducible | |
|
| NaV1.5 | SCN5A | human | LQT Syndrome 3 | HEK | constitutive | |
|
| NaV1.5 duo | SCN5A | human | LQT Syndrome 3 | CHO | constitutive |
|
|
| NaV1.5 big late | SCN5A L409C/A410W | human | LQT Syndrome 3 | HEK 293 | constitutive |
|
|
| NaV1.5 ΔKPQ | SCN5A ΔKPQ | human | LQT Syndrome 3 | HEK | constitutive | |
|
| NaV1.6 | SCN8A | human | Epilepsy / Intellectual disability | CHO | constitutive | |
|
| NaV1.7 | SCN9A | human | Pain | CHO | constitutive |
|
|
| NaV1.7 | SCN9A | human | Pain | CHO | inducible |
|
|
| NaV1.8 | SCN10A/SCN3B | human | Neuropathy | CHO | constitutive |
|
|
| NaV1.9 | SCN11A | human | Pain | HEK | inducible |
|
|