GABA_A (α₁β₂γ₂)

Gene: GABRA1 / GABRB2 / GABRG2

	Standard throughput time	2-4 weeks (draft)
	Source	human
	Expression system	mammalian (LtK, CHO, HEK 293), stable expression
	Method	manual and automated patch-clamping and fluorescence (FlexStation/FLIPR)
	Quality level	high quality functional assay and fluorescence assay
	Reference	positive allosteric modulator: Diazepam
		antagonist: Bicuculline (IC50: 265 nM)
	+  GABAA profiling for pesticides
	+  Antinociceptive screening
	+  Profiling for anticonvulsive / sedative / anxiolytic / memory effects