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Gene: SCN8A
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Standard throughput time | 2-4 weeks (draft) |
| Source | human | |
| Expression system | mammalian (CHO, HEK 293) | |
| Method | manual and automated patch-clamping |
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| Quality level | high quality functional assay |
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| Reference | TTX (IC50: 7.3 µM) |
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| References, further examples | Mibefradil, Lidocaine | |
| + Neuronal sodium channel assay |
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| + Antinociceptive screening (CNS / dorsal root ganglion) | ||
| + CNS toxicity / safety relevant ion channel test |
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